In 2017, many people began to focus on the availability of information regarding APOE. The truth is that genetics can indicate a risk factor for dementia in adulthood. Individuals with Alzheimer's tend to have a family history of the disease, but a very small percentage of people actually inherit the gene mutation that can lead to early-onset Alzheimer's. APOE is more common and refers to late-onset Alzheimer's. Want to learn more about APOE? Keep reading.
What Genes Indicate a Likelihood for Alzheimer's Disease?
Some genes could make it much more likely that you will have Alzheimer's disease at some point in your life. While a genetic disposition is not a guarantee you will develop the disease, it should put you on notice that something could happen.
Late-onset Alzheimer's is most commonly associated with APOE, or apolipoprotein E. This gene comes in several forms. One, which is not common, reduces the risk of the condition. Another increases the risk of Alzheimer's, and one seems to have no effect at all on the condition. You can inherit these genes from both parents, and having more than one of the genes can put you at higher risk for the disease.
Other genes may also have a link to Alzheimer's. They include ABCA7, CLU, and PICALM. As we learn more about these genes, we can figure out better ways to treat and prevent Alzheimer's.
Should You Consider Genetic Testing?
Some people may find the genetic testing to be difficult to conceptualize emotionally. After all, the information can be difficult to contend with if you find out you are very likely to have Alzheimer's in the future. Testing for early-onset Alzheimer's is more helpful than testing for late-onset Alzheimer's because the signs can come on so early and suddenly.
Genetic testing can be difficult to understand, and Alzheimer's can be diagnosed without genetic testing. Ultimately, it is your decision if you want to consider APOE testing, but you should consider that tests could impact your eligibility for long-term care and disability insurance.
If you have fears that Alzheimer's may be present in your family, it does not hurt to discuss the options with your doctor. You may be able to prevent some of the effects with lifestyle changes, and you can also prepare yourself and your family accordingly. Testing is a personal choice, but you may find that having the information is most beneficial for you and your family.
For more information, contact a company that offers APOE genetic services.
Share30 September 2019
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